Oxidation of amines with 2-sulfonyloxaziridines (Davis' reagents).
2-(Phenylsulfonyl)-3-aryloxaziridines (Davis' reagents) react rapidly with amines that are more basic than pyridine to give products that are dependent upon the structure of the amine. Tertiary aliph. amines are oxidized to the corresponding N-oxides in high yields, while secondary aliph. amines giv...
|Journal Title:||Journal of Organic Chemistry Vol. 53; no. 25; pp. 5856 - 5860|
|Authors:||Walter W. Zajac, Thomas R. Walters, Michael G. Darcy|
|Application Date:||Dep. Chem.,Villanova Univ.,Villanova,PA,USA.|
Named reagents and solutions Role: RCT (Reactant), RACT (Reactant or reagent) (Davis' reagents, sulfonyloxaziridines, oxidn. by, of amines)
Amines Role: RCT (Reactant), RACT (Reactant or reagent) (oxidn. of, with sulfonyloxaziridines (Davis' reagents)