Structural studies of a stabilized phosphoenzyme intermediate of Ca 2+-ATPase

Ca2+-ATPase belongs to the family of P-type ATPases and maintains low concentrations of intracellular Ca2+. Its reaction cycle consists of four main intermediates that alternate ion binding in the transmembrane domain with phosphorylation of an aspartate residue in a cytoplasmic domain. Previous wor...

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Journal Title: Journal of Biological Chemistry Vol. 280; no. 18; pp. 18063 - 18072
Authors: David L. Stokes, William J. Rice, Franck Delavoie, Philippe Champeil, David B. McIntosh, Jean-Jacques Lacapere
Format: Article
Published: American Society for Biochemistry and Molecular Biology Inc, 2005
Online Access: Full Text