A Short Synthesis of Morachalcone A

Advanced C-prenylated intermediates for three aromatase inhibitors, including morachalcone A, can be synthesized through a Claisen–Schmidt condensation followed by Florisil®-catalyzed [1,3]-sigmatropic rearrangement of a prenyl phenyl ether.

Journal Title: Tetrahedron Letters Vol. 46; no. 13; pp. 2323 - 2326
Authors: Eduard Casillas, Joseph J. Romano
Format: Article
Published: 03/28/2005
Online Access: Full Text