Fertilization and development of mouse oocytes cryopreserved using a theoretically optimized protocol.

Rational design of a cryopreservation protocol was demonstrated by using theoretical models of the cryopreservation process to develop an optimal freezing protocol for mouse oocytes. A coupled mechanistic model of the processes of freeze-induced cell dehydration and intracellular ice formation was d...

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Journal Title: Human Reproduction Vol. 11; no. 6; pp. 1296 - 1305
Authors: Jens O. M. Karlsson, Ali Eroglu, Thomas L. Toth, Ernest G. Cravalho, Toner Mehment
Format: Article
Language: English
Published: June 1996
Online Access: Full Text