A model of diffusion-limited ice growth inside biological cells during freezing.

A theoretical model for predicting the kinetics of ice crystallization inside cells during cryopreservation was developed, and applied to mouse oocytes, by coupling separate models of (1) water transport across the cell membrane, (2) ice nucleation, and (3) crystal growth. The instantaneous cell vol...

Full description

Journal Title: Journal of Applied Physics Vol. 75; no. 9; pp. 4442 - 4455
Authors: J.O.M. Karlsson, E. G. Cravalho, M. Toner
Format: Article
Language: English
Published: May 1, 1994
Online Access: Full Text